Since 1999, the editors of Technology Review have honored the young innovators whose inventions and research we find most exciting; today that collection is the TR35, a list of technologists and scientists, all under the age of 35. Their work--spanning medicine, computing, communications, electronics, nanotechnology, and more--is changing our world. Synthetic biologist Christopher Voigt has created an unusual image: the Virgin Mary on a lawn of E. coli. In turning microbes into a "photographic" medium, Voigt and his team have illustrated his approach to synthetic biology: creating genetic parts that can be used interchangeably to achieve different results. They hooked a light receptor from blue-green algae to a protein that normally controls E. coli genes' response to the cell's surroundings.